ABSTRACT
Objective:To evaluate the diet quality of patients with Type 2 diabetes mellitus (T2DM) in the community with the Chinese Dietary Balance Index (DBI-16) and to provide a scientific basis for nutrition education.Methods:A random cluster sampling method was adopted to conduct a questionnaire survey of 332 T2DM patients in a community of Bengbu City to obtain demographic sociology and dietary intake information. DBI-16 was used to score and evaluate dietary structure and diet quality.Results:There are low-level under-intake (low bound score =14.0) and excessive intake (high bound score =14.0) in the diet of this population. The degree of excessive intake of men (high bound score =15.0) was higher than that of women (high bound score=13.0) ( Z=-3.12, P<0.01), and the degree of insufficient diet (low bound score =13.0) was lower than that of women (low bound score=15.5)( Z=-2.05, P<0.05). Those with monthly income<1 000 (low bound score =15.5) patients ( χ2 =6.34, P<0.05) and disease course>10 years (low bound score =16.0) had the highest degree of insufficient dietary intake ( χ2 =9.40, P<0.01). Those who did not participate in community health education lectures had significantly higher dietary intake (low bound score =15.0) and imbalance (diet quality distance= 29.0) than those who participated in community health education (low bound score=13.0)(diet quality distance=27.0)( Z=-2.46, P<0.01). According to the score distribution of the DBI-16 index, 73.6% of patients had a severe over-intake of cereals, and only 27.4% and 27.7% had intake of vegetables, fruits, and milk beans that reached the recommended intake. The dietary pattern mainly reflects the existence of a certain degree of excessive dietary intake pattern D. Conclusion:The dietary quality of T2DM patients in Bengbu′s community is in a state of low imbalance. Insufficient and excessive dietary intake coexist and urgently need to be improved.
ABSTRACT
Objective:To observe the changes of glyeemia, urine protein, serum creatinine, blood urea nitrogen and glycosylated hemoglobin in diabetic nephropathy rats and treating effects of Xiaokekang. Methods: Streptozotocin (STZ) was abdominally administered and was feeded by high lipid diet to establish diabetic nephropathy model in rats. Animals were divided into three groups: model group, Xiaokekang treatment group and normal group. Changes in glycemia, serum lipids, serum creatinine, blood urea nitrogen were measured at the 8th, 12th and 16th week after STZ injection. Glycosylated hemoglobin was measured at the 16th weeks after STZ injection. Results: Glycemia, serum lipids, serum creatinine were higher at the 8th, 12th and 16th week compared with normal group. Serum creatinine was higher at the 12th and 16th week, and glycosylated hemoglobin was also highter than that of the normal group. Xiaokekang reduced these changes. Conclusion: Xiaokekang can reduce glycemia, serum lipids and protect renal function.
ABSTRACT
Objective To compare Western blot analysis and immunofluorescence method in Survivin expression. Methods By using Western blot analysis and immunofluorescence method, Survivin gene expressions of the peripheral blood mononuclear cells in 18 patients with leukemia and 10 healthy persons were analysed. Results Positive expression of Survivin gene was detected in 13 of 18 leukemic patients by Western blot analysis and in 11 of 18 leukemic patients by immunofluorescence method. Negative expression of Survivin gene was detected in 10 healthy persons. The results of Survivin expression were the same in 16 patients by Western blots analysis and immunofluorescence method (consistent rate is 88.89%), but the positive expression of Survivin by Western blot analysis was the negative expression by immunofluorescence method in another 2 patients. Conclusion Survivin gene expressed selectively in leukemic cells, but not in normal mononuclear cell in peripheral blood. It indicated that Survivin expression is effective monitoring index in diagnosis and prognosis of leukemia. Survivin expression by Western blot analysis was consistent with immunofluorescence method.